hypocalcemia
Conditions
Interventions
Intervention group:a short-term preoperative administration of calcitriol and calcium: Starting from 2 days before surgery (-2 days), 0.25ug of calcitriol (rosiglitazone), qd, po
Simultaneously calcium carbonate tablets (calcium carbonate D), 600mg, bid, po
Take it for 3 days (including -2 days, -1 days, and 0 days on the day of surgery.
control group:none
Sponsors
Tianjin Medical University Cancer Institute and Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: All of the following must be met to be enrolled in the trial: (1) patients voluntarily participated in this study and signed informed consent; (2) older than 18 years old; (3) diagnosed with bilateral thyroid cancer, simultaneous total thyroidectomy and bilateral central compartment neck dissection should included (with or without lateral neck dissection).
Exclusion criteria
Exclusion criteria: Patients will be excluded if any of the following occurred: (1) previous thyroidectomy and/or central compartment neck dissection; (2) chronic renal failure, acute and chronic nephritis; serum creatinine and urea nitrogen are abnormal at the same time. (3) abnormal parathyroid function; (4) hypercalcemia is found in preoperative examination; (5) previous or current vitamin D overdose or vitamin D toxicity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preoperative calcium;Preoperative inorganic phosphorus;Preoperative PTH;calcium on the first postoperative day;inorganic phosphorus on the first postoperative day;PTH on the first postoperative day;calcium on the second postoperative day;inorganic phosphorus on the second postoperative day;PTH on the second postoperative day;the evaluation of symptomatic hypocalcemia; | — |
Countries
China
Contacts
Public ContactXiangqian Zheng
Tianjin Medical University Cancer Institute and Hospital
Outcome results
None listed