chronic insomnia
Conditions
Interventions
a-wave group:5 Hz frequency taVNS treatment.
?-wave group:10 Hz frequency taVNS treatment.
?-wave group:40 Hz frequency taVNS treatment.
Control group:None
Sponsors
Guang'anmen Hospital China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 55 Years
Inclusion criteria
Inclusion criteria: ?Age between 40 and 55 years old, regardless of gender; ?Right-handedness; ?Meet the diagnostic criteria for IS in the American Diagnostic and Statistical Manual of Mental Disorders, 5th edition; symptoms lasting 3 months or longer; no relevant treatment within the last 2 weeks; ?Previous physical fitness, no psychiatric or neurological abnormalities, no history of traumatic brain injury, history of surgery, etc; ? No contraindications to functional MRI, such as metal placement in the body, claustrophobia, etc; ?The procedure, purpose, potential discomfort and risks of the test were explained to all subjects before the examination, and the subjects voluntarily participated in the study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: ? physical illnesses such as central nervous system disorders, substance abuse, alcohol abuse, and cardiovascular disease; ? other chronic diseases that may affect cognitive function; ?A history of mental illness and family history; ?People with claustrophobia; people with metal residues in the body, deep vein placement, etc. who are unable to perform MRI scans or whose image quality is affected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fMRI;MRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index , PSQI;Hyper-arousal Scale, HAS;Athens Insomnia Scale, AIS;Insomnia Severity Index, ISI;HAMD;HAMA; | — |
Countries
china
Contacts
Public ContactYanping Zhao
Guang'anmen Hospital China Academy of Chinese Medical Sciences
Outcome results
None listed