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Effects of flavanol-rich dark chocolate on visual function and retinal perfusion in children and adolescents: a randomized clinical trial

Effects of flavanol-rich dark chocolate on visual function and retinal perfusion in children and adolescents: a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300071144
Enrollment
Unknown
Registered
2023-05-06
Start date
2023-05-06
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia

Interventions

Experimental group:Eating 14g of dark chocolate
Control group:Eating 4.5g of white chocolate

Sponsors

The Second Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 16 Years

Inclusion criteria

Inclusion criteria: 1: Age 6-16 years old (inclusive) 2: Bilateral myopia, equivalent spherical power (SE) -0.00D to -6.00D (optometry after ciliary muscle paralysis) 3: After cycloplegia, computer optometry was used to detect binocular astigmatism ranging from -0.00D to -1.50D 4: Computer optometry detection of binocular anisometropia after cycloplegia<1.50D 5: Bilateral intraocular pressure = 21mmHg 6: The BMI value is within the normal range of that age group 7: A written informed consent form jointly signed by the child and legal guardian has been obtained

Exclusion criteria

Exclusion criteria: 1: Current or past medical history of dominant strabismus (including intermittent strabismus) and amblyopia in any eye 2: Have a history of any disease or syndrome that may lead to severe myopia (such as Marfan syndrome, Stickler syndrome, retinopathy of premature infants, etc.), including other eye diseases (such as lens diseases such as cataracts, macular degeneration, keratopathy, uveitis, retinal detachment, severe vitreous opacity, nystagmus, etc.) 3: Abnormalities in the refractive interstitial medium of any eye (such as keratoconus, lens conus, spherical lens, etc.) 4: During screening, any eye with intraocular pressure greater than 21mmHg or any eye with glaucoma or angle stenosis or previous medical history 5: Having or having a history of eye injury, the researcher has determined that it is not suitable to participate in this study 6: Any eye with a history of intraocular surgery, strabismus surgery, and eye surgery or laser treatment that affects refractive media or refractive power (such as refractive surgery) 7: Severe systemic illness, which the researchers believe is not suitable for participation in this study 8: Emaciation or obesity 9: Other researchers believe that it is not suitable for enrollment

Design outcomes

Primary

MeasureTime frame
OCT angiography, OCTA;

Secondary

MeasureTime frame
Vision;Contrast sensitivity;Anterior chamber depth; lens thickness;Diopter;

Countries

CHINA

Contacts

Public ContactYan Deng

The Second Affiliated Hospital of Nanchang University

dengyan2@163.com+86 15970464160

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026