Relationship between hepatocyte growth factor and postoperative delirium in elderly patients undergoing joint replacement surgery
Conditions
Interventions
Sponsors
Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: Age =60 years old; Elective total hip replacement or total knee replacement in Shandong University Qilu Hospital (Qingdao)
Exclusion criteria
Exclusion criteria: ? Patients refused or could not complete neurocognitive function assessment; ? History of mental illness or neurological disease; ? Patients who have not completed the screening assessment for dementia and delirium or the assessment results are in dementia or delirium state ? severe hepatic and renal insufficiency ? Preoperative brief assessment of mental state (MMSE) was lower than the required score (illiterate < 17 points; Primary school < 20 points; Secondary school and above < 24 points); ?ASA= Class III; ? Left ventricular ejection fraction < 40% ? Emergency surgery, patients in serious infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hepatocyte growth factor; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-mental State Examination,MMSE;3-minute Diagnostic Interview for CAM, 3D-CAM;Confusion Assessment Method for the Intensive Care Unit, CAM-ICU;Confusion Assessment Method-Severity Score, CAM-S; | — |
Countries
China
Contacts
Public ContactJianjun Li
Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University
Outcome results
None listed