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A case-control study of drug-loaded microsphere and blank microsphere embolization in the treatment of hemoptysis with non-small cell lung cancer

A case-control study of drug-loaded microsphere and blank microsphere embolization in the treatment of hemoptysis with non-small cell lung cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300071106
Enrollment
Unknown
Registered
2023-05-05
Start date
2023-05-05
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer

Interventions

Drug-loaded microsphere group:N/A
Blank microsphere group:N/A

Sponsors

Tianjin Cancer Hospital Airport Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age range from 18 to 70 years old, gender unlimited; 2. According to the guidelines for the Diagnosis and Treatment of primary lung Cancer (2018 Edition), the patient was diagnosed as NSCLC by histopathology; 3. Complete case data; 4. The amount of hemoptysis exceeds 50ml per day; 5. ECOG PS score =2 points; 6. Expected survival > 6 months; 7. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with severe coagulation dysfunction that cannot be corrected; 2. Patients with arteriovenous fistula; 3. Leukocyte 176.8 µmol/L; AST and/or ALT > 2 times the normal upper limit); 5. Patients with active infection requiring antibiotic treatment; 6. Uncontrolled hypertension, diabetes, and cardiovascular disease with obvious symptoms; 7. Allergy to contrast agent; 8. Women with pregnancy or lactation

Design outcomes

Primary

MeasureTime frame
Remission rate and recurrence rate of hemoptysis;

Secondary

MeasureTime frame
1, 3, 6 months objective response rate;1, 3, 6 months disease control rate;Progression Free Survival;Overall Survival;Tumor marker(CEA?SCC?CYFRA21-1);the quality of life scores;ECOG PS score;pain assessment;

Countries

China

Contacts

Public ContactTongguo Si

Tianjin Cancer Hospital Airport Hospital

drsitg@163.com+86 13652089230

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026