Gastric cancer
Conditions
Interventions
Experimental group:Total nutritional formula Food for cancer patients for Special medical Use (IMPACT ORAL)
Sponsors
Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The effects of total nutritional formula food on tumor patients with different types and stages are different for special medical purposes. Appropriate subjects should be selected according to the purpose of clinical research, and patients after radical gastrectomy should be selected. Subjects' inclusion criteria include: (1) Age above 18 years old, under 80 years old, gender unlimited; (2) Patients diagnosed with gastric adenocarcinoma by histology or cytology and treated with radical gastrectomy; (3) Life expectancy exceeds 3 months; (4) Hemoglobin =90g/L; (5) Albumin =2.5g/dL; (6) No blood products were given within 1 week before screening; (7) Those who can tolerate enteral nutrition; (8) Patients can give informed consent, agree to participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) There are serious clinical symptoms, underlying diseases or surgical complications, such as gastrointestinal bleeding and anastomotic fistula, which may jeopardize the development and follow-up of the study; (2) Previous history of gastrointestinal surgery or other digestive tract treatment and influence nutrient absorption; (3) The patient is a pregnant or lactating woman; (4) The patient underwent endoscopic radical gastrectomy; (5) Nutrition should not be ingested orally or through tube feeding before the operation; (6) The patient had participated in another interventional clinical study, including one related to nutritional support, within 4 weeks prior to enrollment; (7) Other malignant neoplasms in the past 5 years (other than those successfully treated basal cell skin neoplasms in situ and cervical neoplasms in situ); (8) Patients who are unwilling or unable to comply with the scheduled visit time and study protocol requirements; (9) Abnormal liver and kidney function (ALT=2 times the upper limit of normal value; Total bilirubin Tbil=2 times the upper limit of normal value; Creatinine Cr=2 times the upper limit of normal); (10) Known to have uncontrolled diabetes mellitus or fasting blood glucose =10mmol/L; (11) The patient had a known history of hypothyroidism or hyperthyroidism; (12) The patient was using fatty milk containing Omega-3 fatty acids, glutamine, thymosin, glucocorticoid, thyroxin, growth hormone, and anti-tumor necrosis factor biologic agents; (13) A known history of allergy to any component of the study product; (14) The patient or family member refuses to sign the informed consent; (15) Uncontrolled mental illness. (16) Patients considered unsuitable for this study by the researcher (such as poor compliance, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum prealbumin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body weight;Fat loss weight, limb skeletal muscle index;Inflammation-related indicators;Immune-related indicators;Metabolism-related index; | — |
Countries
China
Contacts
Public ContactChen Yingtai
Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed