Chronic heart failure
Conditions
Interventions
Vitamin C intervention group:On the basis of conventional treatment of heart failure drugs, vitamin C injection 1000 mg was intravenously dripped daily for 1 week.
control group:Conventional anti heart failure drug treatment.
Sponsors
Hanzhong Central Hospital, Shaanxi province,China.
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Hospitalized patients who had chronic heart failure with NYHA class III or IV; 2. The patient has symptoms and signs of chronic heart failure; 3.. NT-proBNP>125 pg/mL. 4. Aged over 18 years old; 5. Patients who agree and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who had a history of chronic kidney disease, diabetes, hypothyroidism, hyperthyroidism, acute or chronic infection, chronic liver, pregnancy,cancer,and high alcohol intake were excluded from the the study; 2. Patients combined with severe primary or secondary diseases of other systems; 3. Patients have been using biological agents within 3 months; 4. Patients who are unsuitable for this clinical trial considered by researchers; 5. Patients who with poor compliance were excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum vitamin C levels;Serum Endothelin-1 (ET-1);Urinary microalbumin ;serum nitric oxide level;serum pro-BNP; | — |
Countries
China
Contacts
Public ContactGeng Like
Hanzhong Central Hospital
Outcome results
None listed