Hypothyroxemia in the first trimester
Conditions
Interventions
Exposed group:None
Control group:None
Sponsors
Shanghai First Maternity and Infant Hospital, School of Tongji University
Eligibility
Sex/Gender
Female
Age
18 Years to 42 Years
Inclusion criteria
Inclusion criteria: 4 to 14 weeks gestation;18 years of age =42 years of age; The exposure group met the diagnostic criteria for hypothyroxinemia: normal TSH and FT4 was lower than the 5th percentile. The control group was pregnant women with normal thyroid function. No personal history of thyroid-related diseases: hyperthyroidism, hypothyroidism, Subclinical hypothyroidism, partial or total thyroidectomy, after iodine-131 treatment; There are no diseases that can lead to spontaneous abortion, such as balanced chromosomal translocation in couples, uterine malformations, uncontrolled hypertension, diabetes, autoimmune diseases (such as systemic lupus erythematosus, connective tissue disease, antiphospholipid syndrome, etc.).
Exclusion criteria
Exclusion criteria: Without no plan to give birth; Patients who could not be followed up; Ectopic pregnancy; Pregnant women who develop other thyroid diseases requiring medical intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fetal survival rate at 28 weeks of gestation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fetal survival rate at 12 weeks of gestation; | — |
Countries
China
Contacts
Public ContactLiguohua
Shanghai First Maternity and Infant Hospital
Outcome results
None listed