Thyroid disease
Conditions
Interventions
I group:Intraoperative Intravenous Bolus Dose of Dexmedetomidine0.8µg/kg at Pre-induction intervention group for general anesthesia
A group:Intraoperative Intravenous Bolus Dose of Dexmedetomidine0.8µg/kg at Pre-awakening intervention group of general anesthesia
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily participate in this study and sign the relevant informed consent; 2. Elective Radical Thyroidectomy; 2. Age 18-65 years; 3. American Society of Anesthesiologists (ASA) classification I-II; 4. BMI:18.5-30.0 kg/m2.
Exclusion criteria
Exclusion criteria: 1. History of thyroid surgery 2. Patients with recent childbearing plans and pregnant or lactating women 3. Preoperative blood routine, liver function electrolyte and examination results were significantly abnormal 4. Patients with coronary heart disease, severe hypertension, diabetes, and severe heart block 5. Alcohol and opioid abusers or long-term opioid users 6. Participants in other clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Medial forearm pain threshold; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of recovery;Postoperative analgesic drug use;Postoperative pain score; | — |
Countries
China
Contacts
Public ContactGao Fang
Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed