polycystic ovary syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.PCOS and infertility were diagnosed PCOS is diagnosed according to Rotterdam consensus as fulfilling at least two of the three criteria: (1) oligo-anovulation or anovulation; (2) clinical or biochemical signs of hyperandrogenism; and (3) polycystic ovarian morphology on ultrasound, as defined by at least one ovary with 12 follicles or volume 10 ml. 2.Infertility due to PCOS,amenorrhea and ovulation disorder,at least one of the fallopian tubes is unobstructed,there are indications of out-patient expulsion promotion,and no contraindication of expulsion promotion (1)To induce ovulation to guide cohabitants (2)intrauterine artificial insemination with ovulation induction 3.PCOS intended to receive CET(IVF/ICSI/PGT)for endometrial preparation with LE stimulation due to irregular menstruation and ovulation disorder 4.=38 years of age at oocyte retrieval; 5.She has not used LE/CC and other efflux stimulating drugs in the last 3 months.
Exclusion criteria
Exclusion criteria: 1.Outpatient platoon promotion and AIH patients: (1)bilateral tubal obstruction (2)marriage without normal sex life. (3)male azoospermia 2.Uterine malformations or abnormalities:double uterus,mediastinal uterus(complete or incomplete),moderate to severe uterine adhesions,etc; 3.History of unilateral or bilateral ovarian surgery; 4.History of recurrent abortion 5.Chromosomal abnormalities in one or both partners(except chromosomal polymorphism)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dominant follicle rate(First period);Ovulation rate after trigger(First period); | — |
Secondary
| Measure | Time frame |
|---|---|
| Expulsion cycle cancellation rate(First period);ovulation rate(First period);clinical pregnancy rate(First period);Biochemical pregnancy rate(First period);Early/late abortion rate(First period);Multiple pregnancy rate(First period);OHSS rate(First period);Intimal thickness(First period);Intimal morphology(First period);LUFS rate(First period);Malformation rate(First period);Cumulative dominance number of follicles;Cumulative ovulation rate;Cumulative biochemical pregnancy rate;Cumulative clinical pregnancy rate;Cumulative early/late abortion rate;Cumulative live birth rate;Cumulative multiple pregnancy rate;Cumulative OHSS rate;Cumulative LUFS rate;Live birth rate(First period); | — |
Countries
China
Contacts
Ningxia Medical University General Hospital