Bladder cancer
Conditions
Interventions
Gold Standard:pathological diagnosis, Urine exfoliative cytology
Index test:Bladder cancer methylation genes, bladder cancer urine microbes
Sponsors
The First Affiliated Hospital of Naval Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Case Group (1) Age above 18 years old; (2) Understand the purpose of the experiment, sign the informed consent form, and provide 100ml of morning urine; (3) Patients with clinical suspicion of bladder cancer (including bladder cancer originating from urothelium, renal pelvis cancer, ureteral cancer, etc.); (4) Consent to undergo urine cytology examination and have a clear examination report (the pathological report of other hospitals or our hospital can be used). 2. Control group (1) Age above 18 years old; (2) Understand the purpose of the experiment, sign the informed consent form, and provide 100ml of morning urine; (3) Healthy people or patients with clinically diagnosed benign diseases of urinary system, including urolithiasis, renal cyst, ureteral stricture, urethral stricture, hypospadias, benign prostatic hyperplasia, urinary tract infection, chronic prostatitis, cystitis glandalis, etc. 3. Interference group (1) Age above 18 years old; (2) Understand the purpose of the experiment, sign the informed consent form, and provide 100ml of morning urine; (3) Patients with other tumors that were clinically or pathologically diagnosed as non-bladder cancer, including prostate cancer, renal cancer, ureteral cancer, renal pelvis cancer, etc.
Exclusion criteria
Exclusion criteria: 1. Unwillingness to sign informed consent; 2. Pregnant women; 3. Patients with tumors at two or more sites; 4. Patients who could not be diagnosed clinically or pathologically; 5. Patients with radiotherapy and chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| methylation of gene; microbiology ; | — |
Secondary
| Measure | Time frame |
|---|---|
| ROC curve; | — |
Countries
China
Contacts
Public ContactZhang zhensheng
The First Affiliated Hospital of Naval Medical University
Outcome results
None listed