LBBB and HF with mild reduced LVEF
Conditions
Interventions
LBBP group:N/A
Sponsors
Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University,
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Patients with typical left bundle branch block (LBBB). Definition of LBBB: Strauss definition criteria include QRS duration = 140 ms (male) = 130 ms (female), QRS dent or blur in two or more adjacent V1, V2, V3, V4, V5, V6, I and AVL leads, QS or RS in V1 and V2. 2) Patients with Heart failure symptom: Clinical symptoms of chest tightness and shortness of breath; Exclude others requiring coronary angioplasty; After more than 3 months of drug treatment; Cardiac ultrasound (LVEF) < between 50% (eg, baseline 60% < LVEF (ECHO) < 50%, and the gold standard LVEF (including short-axis LVEF and long-axis LVEF) < less than 50% can be enrolled by cardiac magnetic resonance. 3) Patients aged 18 and above. 4) Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients who cannot participate in follow-up for reasons. 2) Active infection. 3) Women who are expected to become pregnant or breastfeeding within 1 year. 4) Participated in other clinical trials within the last 3 months. 5) Poor compliance, unable to strictly implement the scheme. 6) Vulnerable groups, including mental illness, cognitive impairment, critically ill patients, minors, pregnant women, students / subordinates of PI or researchers, employees of research units or sponsors, etc. 7) Any other circumstances that the investigator considers unsuitable for participation in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac echo; | — |
Secondary
| Measure | Time frame |
|---|---|
| MIBI-18PDG; | — |
Countries
China
Contacts
Public ContactGuosheng Fu
Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University
Outcome results
None listed