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Exploration of the application value of HPV-ctDNA test for vulvar carcinoma after surgery: a prospective cohort study

Exploration of the application value of HPV-ctDNA test for vulvar carcinoma after surgery: a prospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070947
Enrollment
Unknown
Registered
2023-04-26
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vulvar carcinoma

Interventions

Group of vulvar carcinoma:None

Sponsors

Zhujiang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Age =18 years old; 2. Newly treated patients did not receive therapeutic surgery, radiotherapy and chemotherapy (except tissue biopsy); 3.FIGO staging was clear, patients who were ready for surgery at stage IA-IIIC were treated with surgery regardless of whether they received subsequent radiotherapy or concurrent chemoradiotherapy (data from NCT00006096, tumor T1-T3 was treated with surgery according to the NCCN guidelines, corresponding to FIGO?a-?c); 4.Primary squamous cell vulvar carcinoma; 5. Clear HPV typing, type 16 and/or 18 infection; 6. Receiving standard surgery and/or radiotherapy and chemotherapy for radical treatment, regardless of lymph node involvement;7. Participate voluntarily and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with benign or precursor lesions of the vulva (Vin-vulvar intraepithelial neoplasia);2. Patients with non-squamous lesions of the vulva (such as melanoma);3. Patients with verrucous vulvar carcinoma;4. Patients with recurrent squamous cell vulvar carcinoma only received surgical resection; 5. Patients with secondary tumors.

Design outcomes

Primary

MeasureTime frame
HPV ctDNA;

Countries

China

Contacts

Public ContactYiFeng Wang

Zhujiang Hospital of Southern Medical University

wyf1988@163.com+86 13825013170

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026