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Effect of albuterol premedication on the occurrence of respiratory adverse events in congential scoliosis children undergoing primary posterior fusion and hemivertebra resection: a double-blind, randomized controlled trial

Effect of albuterol premedication on the occurrence of respiratory adverse events in congential scoliosis children undergoing primary posterior fusion and hemivertebra resection: a double-blind, randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070934
Enrollment
Unknown
Registered
2023-04-26
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Scoliosis

Interventions

Experimental group:Treatment is administered at least 20minutes preoperatively to ensure maximal bronchodilation. In cases of unanticipated theatre delays, salbutamol is readministrated the 20minutes
contorl group:Equal volume of saline is delivered in the same way as those in experimental group.

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 14 Years

Inclusion criteria

Inclusion criteria: (1) Congential scoliosis children, 2-14 years old, undergoing primary posterior fusion and hemivertebra resection. (2) ASA grade: I-II (3) Parents understand and consent to participate in this study (4) Written informed consent is needed before enrollement.

Exclusion criteria

Exclusion criteria: (1) Premedication: midazolam?atropine?ketamine (2) Abnormal airway anatomy (3) Preoperative respiratory failure?congenital heart disease (4) Participate in other study at the same time (5) Parents' refuse (6) Postpone of the operation due to upper airway infection (7)Plan of admission to ICU (8) Patients who does not have osteomy , or patients who only have growing-rod implantation or the growing rod lengthening surgery

Design outcomes

Primary

MeasureTime frame
the occurrence of perioperative respiratory adverse events ;

Secondary

MeasureTime frame
unplanned admission to ICU;the occurrence of postoperative complications;length of hospital stay postoperatively;

Countries

China

Contacts

Public ContactMa Lulu

Peking Union Medical College Hospital

malulupumch_6@163.com+86 13811049619

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026