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Clinical effect of midazolam oral solution on antianxiety/sedation in adults before surgery

Clinical effect of midazolam oral solution on antianxiety/sedation in adults before surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070925
Enrollment
Unknown
Registered
2023-04-26
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patient was anxious and nervous before the operation

Interventions

Midazolam group:none
Non midazolam group:none

Sponsors

The Fourth Affiliated Hospital Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1: Aged 18-65 years 2: deviation from the ideal weight =25% 3: ASAI-II 4: Operation duration less than 2 hours (such as appendectomy, abortion operation, crazy repair and other short operations): 5: no history of long-term use of analgesia, sedation, antianxiety drugs

Exclusion criteria

Exclusion criteria: 1: Patients with known allergy to midazulam or benzodiazepines, acute closed-eye glaucoma or open-angle glaucoma without effective treatment 2: the body weight exceeds 25 percent of the ideal body weight 3: any serious systemic organ disease (cardiopulmonary/kidney/liver), neurological disease (cerebral palsy, autism, etc.), or the use of anesthetics or other central nervous system inhibitors 4: Patients who have taken any medication that may interfere with the pharmacokinetics or pharmacodynamics of midazulam, such as antifungal agents, macrocyclic acetoantibiotics, cimetidine, rifamycin, or calcium channel blockers 5: Patients with communication disorders, cognitive dysfunction, and a history of mental illness 6: pregnant 7: Subjects considered unsuitable for this study by the researcher

Design outcomes

Primary

MeasureTime frame
Vital sign;

Secondary

MeasureTime frame
Ramsay score;Overall satisfaction rating;

Countries

China

Contacts

Public ContactCao Zhang

The Fourth Affiliated Hospital Zhejiang University School of Medicine

bioger@126.com+86 15858931168

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026