The patient was anxious and nervous before the operation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1: Aged 18-65 years 2: deviation from the ideal weight =25% 3: ASAI-II 4: Operation duration less than 2 hours (such as appendectomy, abortion operation, crazy repair and other short operations): 5: no history of long-term use of analgesia, sedation, antianxiety drugs
Exclusion criteria
Exclusion criteria: 1: Patients with known allergy to midazulam or benzodiazepines, acute closed-eye glaucoma or open-angle glaucoma without effective treatment 2: the body weight exceeds 25 percent of the ideal body weight 3: any serious systemic organ disease (cardiopulmonary/kidney/liver), neurological disease (cerebral palsy, autism, etc.), or the use of anesthetics or other central nervous system inhibitors 4: Patients who have taken any medication that may interfere with the pharmacokinetics or pharmacodynamics of midazulam, such as antifungal agents, macrocyclic acetoantibiotics, cimetidine, rifamycin, or calcium channel blockers 5: Patients with communication disorders, cognitive dysfunction, and a history of mental illness 6: pregnant 7: Subjects considered unsuitable for this study by the researcher
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vital sign; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ramsay score;Overall satisfaction rating; | — |
Countries
China
Contacts
The Fourth Affiliated Hospital Zhejiang University School of Medicine