liver tumor
Conditions
Interventions
the group of hydromorphone:After successful subarachnoid puncture, 75 ug hydromorphone is administrated.
the group of morphine:After successful subarachnoid puncture, 150ug morphine is administrated.
Sponsors
Sir Run Run Shaw Hospital (SRRSH), affiliated with the Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists physical status I and II; 2. patients scheduled for laparoscopic liver resection surgery; 3. age between 18-75; 4. body mass index <=30 kg/m2; 5. Volunteered to participate in this study, and signed informed consent was obtained
Exclusion criteria
Exclusion criteria: 1. Hypersensitivity to hydromorphone and morphine or its excipient ingredients; 2. Had contraindications to spinal anesthesia; 3. Had taken or were recently taking opioids, non steroidal anti-inflammatory drugs 48 h before surgery 4. Had severe cardiocerebral hepatic and renal dysfunction, bronchial asthma, endocrine disease, dysuria, ileus as well as severe infectious disease; 5. Suspected or true history of alcohol, drug abuse; 6. History of substance abuse, chronic pain and psychiatric disorders, other concurrent diseases in pregnancy; 7. Refusal of analgesic pump; 8. Had participated in other clinical studies within 3 month; 9. Vulnerable populations, including those with psychiatric disorders, cognitively impaired, critically ill, pregnant, illiterate, etc
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first compression of analgesic pump; | — |
Countries
China
Contacts
Public ContactChunyan Yan
Sir Run Run Shaw Hospital (SRRSH), affiliated with the Zhejiang University School of Medicine
Outcome results
None listed