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A clinical study on the evaluation of the efficacy of buried thread method based on dynamic sensing monitoring of abdominal pressure in patients with brainstem medulla oblongata lesions with abdominal distension

A clinical study on the evaluation of the efficacy of buried thread method based on dynamic sensing monitoring of abdominal pressure in patients with brainstem medulla oblongata lesions with abdominal distension

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070867
Enrollment
Unknown
Registered
2023-04-25
Start date
2022-01-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brainstem medulla oblongata lesions

Interventions

Control group:Standard Program
Observation group:The buried thread method with Yu's points

Sponsors

Guangdong 999 Brain Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients aged >=18 years with brainstem (medulla oblongata) lesions diagnosed by cranial CT or MR ; abdominal distension or naked eye visible abdominal bulge after the use of mechanical ventilation; difficulty in defecation, percussion abdominal bulge, diminished (12 mmHg ; those with a nutritional tolerance score >=2; hemodynamic stability ; patient's family signed an informed consent form. (Note: All inclusion criteria were met to be included.) The brainstem consists of three parts: the medulla oblongata, pons, and midbrain, and lesions in any of these parts (vascular lesions, tumors, infectious and demyelinating diseases) are collectively referred to as brainstem lesions [15]. Commonly, brainstem infarction, brainstem hemorrhage, brainstem inflammation, brainstem or tumor, and optic neuromyelitis optica are involved. Criteria for hemodynamic smoothness: ? heart rate P > 45 beats/min; ? respiration 9-34 breaths/min; systolic blood pressure (SBP) >= 110 or 60 mmHg.

Exclusion criteria

Exclusion criteria: Exclusion criteria: Those who are <18 years old or =85 years old, unable to complete high-resolution examination results or unable to analyze whether it is a brainstem lesion due to many interfering factors. Diagnosis confirmed as intestinal obstruction or abdominal distension caused by organic lesions of the intestine such as rectum and colon (e.g., tumors, colon polyps, etc.); the presence of open abdominal wounds or abdominal wounds that have not healed and other contraindications to burial; serious infections, bleeding tendencies, coagulation abnormalities and other factors that may cause adverse reactions to burial; (Note: Excluded if any of the exclusion criteria are met.)

Design outcomes

Primary

MeasureTime frame
Intra-abdominal pressure;

Secondary

MeasureTime frame
Abdominal circumference;

Countries

CHINA

Contacts

Public ContactZhao Anna

Guangdong 999 Brain Hospital

109545437@qq.com+ 86 15814832989

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026