Study on the effect and regulation mechanism of probiotics on microenvironment of infected wound after open fracture surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300070801

Enrollment

Unknown

Registered

2023-04-23

Start date

2023-05-01

Completion date

Unknown

Last updated

2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open fracture

Interventions

Postoperative wound infection group/no wound infection group:None

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Open fracture confirmed by imaging examination; The age range from 18 to 80; Good communication and understanding skills; The subjects consented to participate in the study voluntarily.

Exclusion criteria

Exclusion criteria: Disorder of consciousness or history of mental illness; Associated with other infectious diseases; Complicated with malignant tumor, serious endocrine and hematological diseases; Complicated with heart, liver, kidney and other organ dysfunction; Pregnant or lactating women; Oral antibiotics within 1 month before surgery; Long-term use of immunosuppressive agents or microbial agents.

Design outcomes

Primary

Measure	Time frame
Diversity of wound flora;Abundance of wound flora;	—

Secondary

Measure	Time frame
Blood cell classification;	—

Countries

China

Contacts

Public ContactLi ka

West China Hospital, Sichuan University

779011794@qq.com+86 17844615785

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026