A cohort study of visceral fat accumulation caused by high-dose folic acid supplementation in the first trimester to affect the risk of gestational diabetes

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300070781

Enrollment

Unknown

Registered

2023-04-23

Start date

2023-05-01

Completion date

Unknown

Last updated

2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational diabetes mellitus

Interventions

Early pregnancy intake of high-dose folic acid group:N/A

Early pregnancy non high-dose folic acid group:N/A

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1: Archived prenatal examination in the study hospital, and the first prenatal examination is 9-14 weeks gestation; 2: 18 years old and above; 3: Pregnant women living in the city.

Exclusion criteria

Exclusion criteria: 1: Multiple pregnancy; 2: No clear time of last menstrual period; 3: liver, kidney and other endocrine diseases; 4: Combined with heart, cerebrovascular diseases and other important organ dysfunction; 5: Those who are unable to complete follow-up as prescribed.

Design outcomes

Primary

Measure	Time frame
folic acid;Red blood cell folate;serum folic acid;Vitamin B-12;homocysteine;Methylmalonic acid;5-Methyltetrahydrofolate;ferritin;	—

Countries

China

Contacts

Public ContactLi Guoju

Qingdao Women and Children's Hospital

liguojuhaha@126.com+86 15653258275

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026