Mild Cognitive Impairment
Conditions
Interventions
Experimental group:Give the subjects oral administration of sodium ferulate tablets, one tablet per time, three times a day, for 100 consecutive days
Regular follow-up and clinical symptom observation and evaluation.
Control group:Give the subjects oral administration of placebo tablets, one tablet per time, three times a day, for 100 consecutive days
Sponsors
the 71st Group Army Hospital of CPLA Army
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: ?complained of memory loss and confirmed by others; ?Clinical evaluation confirmed cognitive impairment, impairment of logical memory such as delayed story recall (DSR) score at least 1.5 SD lower than the average of age - or education-matched population, other cognitive areas remained relatively intact and did not meet the criteria for dementia; ?The score of mini-mental state examination ( MMSE ) was between 24 and 30; ?Clinical Dementia Rating Scale ( CDR ) = 0.5, amnestic CDR scale memory item score at least 0.5 ; ?Activities of daily living intact or very slight impairment, such as instrumental activities of daily living (IADL) score of 16 or greater; ?No dementia.
Exclusion criteria
Exclusion criteria: ?Those who do nry of severe cerebrovascular disease; ?Those with a history of deot meet the above inclusion criteria; ?patients with a histopression within 2 years; ?patients with severe allergic diseases such as allergic shock ; ?patients with alcohol, mental drug abuse or dependence within 2 years ; ?Patients who had taken anticholinergic drugs, antidepressants, ginkgo biloba preparations before this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA);Alzheimer’s Disease Assessment Scale-Cognitive Section (ADAS-cog);Delayed Story Recall (DSR);Mini-mental State Examination (MMSE);Activity of Daily Life ( ADL);Clinical Dementia Rating (CDR);clinical efficacy; | — |
Countries
China
Contacts
Public ContactHong Qian
the 71st Group Army Hospital of CPLA Army
Outcome results
None listed