COVID-19
Conditions
Interventions
experimental group:micro-hyperbaric oxygen therapy + routine isolation course
Sponsors
Naval Medical Center of PLA
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18~75 years old 2. Positive SARS-CoV-2 nucleic acid test 3. Nucleic acid test positive for 8 days or longer 4. Able to complete the operation of the micro hyperbaric chamber as required under guidance 5. No absolute contraindication to hyperbaric exposure 6. Sign the informed consent form
Exclusion criteria
Exclusion criteria: Patients with multiple rib fractures, severe and extensive chest wall contusions and untreated open chest wall trauma; (2) Tension pneumothorax and spontaneous pneumothorax in untreated patients; (3) Severe obstructive pulmonary emphysema patients; (4) Patients with uncontrolled acute respiratory obstruction; (5) Patients with active tuberculosis with cavity formation or still hemoptysis; (6) Patients with recently extracted teeth such as maxillary molars or cuspids; (7) Patients with purulent otitis media; (8) Non-congestive glaucoma patients; (9) Patients with retinal detachment; (10) Those with internal bleeding or uncontrolled bleeding disorders; (11) Untreated cancer patients. 2. Pregnant women. 3. Claustrophobic patients. 4. COVID-19 asymptomatic patients 5. Patients considered unsuitable for the trial for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of sarS-COV-2 nucleic acid test turning negative; | — |
Secondary
| Measure | Time frame |
|---|---|
| Viral load (CT value);Routine blood;Interleukin-1ß;Interleukin-6;C-reactive protein;TNF-a;D-dimer (D2D);Serum IgE;Serum IgG;Fatigue Self-Rating Scale for Fatigue;The Baker Anxiety Scale for anxiety;The Baker Depression Scale for depression; | — |
Countries
China
Contacts
Public ContactYang Liu
Naval Medical Center of PLA
Outcome results
None listed