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Effect of intraoperative dexamethasone on pulmonary complications after thoracic surgery: a randomized, controlled, double-blind trial

Effect of intraoperative dexamethasone on pulmonary complications after thoracic surgery: a randomized, controlled, double-blind trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070769
Enrollment
Unknown
Registered
2023-04-23
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary Complications

Interventions

Dexamethasone group:Give 10mg of dexamethasone (2ml)
Control group:Provide equal volume of physiological saline (2ml)

Sponsors

Qilu Hospital of Shandong University (Qingdao)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients diagnosed with lung cancer and undergoing elective lung surgery under general anesthesia

Exclusion criteria

Exclusion criteria: Emergency surgery, age less of 20 ys, pregnancy, uncontrolled diabetes patients, preoperative infection, long-term use hormones, using other hormone drugs during surgery, and severe cardiopulmonary disease. The researchers judged that patients who were not involved in the experiment were considered inappropriate.

Design outcomes

Primary

MeasureTime frame
The incidence of Postoperative pulmonary Complications;

Secondary

MeasureTime frame
atelectasis;Respiratory failure;pleural effusion;pneumonia;bronchospasm;pulmonary congestion;pneumothorax;Unplanned noninvasive or invasive ventilation;Composite respiratory complications during hospital stay;Pulmonary embolism;Acute respiratory distress syndrome;Systemic inflammatory response syndrome;Sepsis;Acute kidney injury;surgical-site infection;Unplanned ICU admission;Length of hospital stay;In-hospital mortality;Postoperative nausea or vomiting;Postoperative pain score;Postoperative inflammatory factor index;Preoperative hemoglobin;Postoperative hemoglobin;Postoperative neutrophils to lymphocytes;C-reactive protein;Preoperative Arterial blood gas analysis;

Countries

China

Contacts

Public ContactWenyuan Lyu

Qilu Hospital (Qingdao) of Shandong University

lwyjerry@163.com+86 18561811387

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026