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Alfentanil plus dexmedetomidine for sedation in transesophageal echocardiography

Alfentanil plus dexmedetomidine for sedation in transesophageal echocardiography

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070765
Enrollment
Unknown
Registered
2023-04-23
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sedation for transesophageal echocardiography

Interventions

Control group:One dyclonine was given orally, midazolam 1mg was given intravenously, and dexmedetomidine was pumped at a rate of 1.5× ideal body weight ml/h
Experimental group:Alfentanil 8µg/kg was given intravenously and dexmedetomidine 1.5× ideal body weight ml/h was given by pump

Sponsors

People's Hospital of Shiyan CIty
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18 to 80 years, applying for TEE examination in our hospital. 2.ASA grade I-III. 3. Subjects were willing to join in the study, sign the informed consent, good adherence,and cooperat with follow-up.

Exclusion criteria

Exclusion criteria: 1. History of allergic reaction to the medications used in this study. 2. suspected or confirmed pregnancy. 3. Severe neurological or mental disorder. 4. Heart rate 1.5).

Design outcomes

Primary

MeasureTime frame
Whether sedation is adequate (inadequate sedation is defined as a pharyngeal reflex grade of 3 or greater);

Secondary

MeasureTime frame
The difficulty of inserting the probe;Blood pressure;heart;Oxygen saturation;Respiratory rate;Number of remedy medications;Patient satisfaction;Physician satisfaction;Dosage of drugs used;Modified Aldrete scores;Ramsay;

Countries

CHINA

Contacts

Public ContactRan Ran

People's Hospital of Shiyan CIty

ranran1146@163.com+86 18671910918

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026