cerebral apoplexy
Conditions
Interventions
Intensive blood pressure group:Vasoactive drugs
Standard blood pressure group:The dose of continuous infusion was adjusted on the basis of changes in vital signs, with the safety threshold of 110 to 140 mm Hg for systolic blood pressure control by
Sponsors
Shanghai Changhai Hospital Anesthesiology Department
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Subjects must meet all the following criteria to be eligible for inclusion in the study: 1) Adult (age =18 years old) 2) The clinical diagnosis is acute ischemic stroke, and the imaging proves that it is great vascular occlusion (anterior circulation or posterior circulation). 3) mechanical embolectomy was performed within 24 hours after the onset of stroke. 4) mechanical embolectomy under general anesthesia 5)ASA classification: II-III. 6) BMI: 18.5 to 30kg/m2. 7) Sign the informed consent form (or agent signing)
Exclusion criteria
Exclusion criteria: Potential subjects will be excluded from this study if they meet any of the following criteria: 1) The responsible physician's judgment on the benefits of treatment is unclear (such as late dementia, severe disability in the past or extremely short life expectancy after embolectomy). 2) There are other diseases that interfere with clinical efficacy or follow-up evaluation (such as tumor, chronic airflow disease, severe heart failure, and definite post-stroke disability (mRS 3-5)). 3) allergic to any narcotic drugs or any other auxiliary materials 4) transplant surgery or transplant patients 5) Patients with aortic isthmus stenosis and arteriovenous shunt (except: patients with hemodynamic inactive dialysis shunt) 6) Lactating women 7) currently participating in other clinical trials and affecting the clinical prognosis evaluation. 8) heart, lung, liver, kidney and other important organ dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRS score at 90 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| ICH;Image endpoint;Postoperative outcome; | — |
Countries
China
Contacts
Public Contactlibinben
Shanghai Changhai Hospital Anesthesiology Department
Outcome results
None listed