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Effect of dexmedetomidine combined with ropivacaine for erector spinal nerve block on perioperative opioids administration in thoracotomy

ffect of dexmedetomidine combined with ropivacaine for erector spinal nerve block on perioperative opioids administration in thoracotomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070750
Enrollment
Unknown
Registered
2023-04-21
Start date
2023-04-21
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracotomy

Interventions

Intervention Group:dexmedetomidine combined with ropivacaine
Control Group:ropivacaine

Sponsors

Yi Du Central Hospital of Wei Fang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Undergo elective thoracotomy; Aged 18-80 years; Patients with ASA grades I-III; Agreed to participate in this study and signed informed consent.

Exclusion criteria

Exclusion criteria: Patients allergic to study drug; Contraindications to nerve block; Severe spinal deformity; Were using opioid or nonopioid analgesics; Peripheral or central nervous system disorders (including chronic pain); Severe renal impairment (those requiring renal replacement therapy); Severe hepatic impairment (child Pugh class C); IBM(body mass index)>40kg/m2 Unable to communicate preoperatively due to coma, speech disturbance, or severe dementia.

Design outcomes

Primary

MeasureTime frame
Intraoperative remifentanil administration;Postoperative opioid consumption;—

Secondary

MeasureTime frame
Intraoperative propofol administration;qNOX;qCON;Plasma stress responses factor levels;Postoperative pain score;Incidence of postoperative nausea and vomiting;Complications within 30 days after surgery;30 day postoperative all-cause mortality;The incidence of chronic pain after surgery is 3 months after surgery;—

Countries

China

Contacts

Public ContactHua yong Chen

Yi Du Central Hospital of Wei Fang

7658053@qq.com+86 13964788382

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026