perioperative s-ketamine forchronic postoperative pain after breast cancer surgery

perioperative s-ketamine for chronic postoperative pain after breast cancer surgery - s-ketamine and chronic postoperative pain

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300070728

Enrollment

Unknown

Registered

2023-04-21

Start date

2023-05-01

Completion date

Unknown

Last updated

2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brest cancer

Interventions

s-ketamine :s-ketamine

control:saline

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ? Age (18-60) years old; ? Body mass index (BMI) (18 ~ 25) kg/?; ? American Standards Association (ASA) ?-? Classification. ? Radical mastectomy (including axillary lymph node dissection, sentinel lymph node biopsy and breast reconstruction after mastectomy) is planned under general anesthesia.

Exclusion criteria

Exclusion criteria: ? Patients with heart, brain, lung, liver, kidney and other major organ diseases; ? Allergic to esketamine and other experimental drugs; ? Patients with chronic pain before surgery; (4) Alcohol and drug abuse; ? Psychiatric history, language communication disorder, unable to understand the content of the experiment.

Design outcomes

Primary

Measure	Time frame
chronic postoperative pain;	—

Secondary

Measure	Time frame
postoperative pain;depression;	—

Countries

china

Contacts

Public Contactzhang xi

Renmin Hospital, Hubei University of Medicine, Shiyan Hubei

xyzgmm@163.com+86 18772212334

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026