Dry eye disease
Conditions
Interventions
Gold Standard:Patients who met the following two criteria
a) Patients with complaint of dryness, foreign body sensation, burning, eyestrain, redness and impaired vision, OSDI=13, FBUT=5s or Schrimer I
Index test:Matrix Metalloproteinase 9 detection kit (colloidal gold method)
Sponsors
Xiangyang No.1 People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Subject gender, age were not limited, and clinical background information was complete (including patient ID number, medical record number, gender, age, disease history, clinical diagnosis background information, etc.); (2) Voluntarily participated in the study and signed an informed consent form, or signed an informed consent form by a legally authorized representative; (3) Patients, suspected population in the onset phase of dry eye disease; (4) The patient complained of ocular dryness, foreign body sensation, burning sensation, fatigue, discomfort, redness of the eye, fluctuation of vision and other subjective symptoms. Note: articles (1) and (2) must be satisfied and then any one of (3) to (4) can be enrolled.
Exclusion criteria
Exclusion criteria: (1) Unable to cooperate with the investigator for severe mental disorder or language disorder sampled subjects; (2) Patients who have been enrolled in this clinical trial; (3) Subjects voluntarily dropped out or could not complete for various reasons; (4) The clinical diagnoses were active allergic conjunctivitis, having undergone inner and outer eye surgery in January, having suffered from trauma to the eye in January, having a history of contact lens wearing in January, pregnancy status, or the presence of any ocular infectious disease. (5) Patients for whom the investigator considered it inappropriate to participate in this clinical trial for various other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMP-9 in the human ocular surface rinsing fluid ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Positive predictive value;Negative predictive value;Total consistent rate; | — |
Countries
China
Contacts
Public ContactYang Jinbo
Xiangyang No.1 People's Hospital
Outcome results
None listed