Indeterminate Biliary Strictures
Conditions
Interventions
dual-lumen catheter-guided mini-forceps biopsy is performed first:In ERCP procedures, catheter-guided mini-forceps biopsy is performed before biliary brush cytology.
Biliary brush cytology with vacuum aspiration is performed first:In ERCP procedures, biliary brush cytology with vacuum aspiration is performed before dilation catheter-guided mini-forceps biopsy.
Sponsors
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 88 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18-88 years old; 2. Willing and able to comply with the study procedures and provide written informed consent to participate in the study. 3. Biliary obstructive symptoms,or indeterminate biliary stricture suspected to be intrinsic based on prior imaging; 4. With ERCP indications.
Exclusion criteria
Exclusion criteria: 1. Those who cannot tolerate endoscopy; 2. Patients with contraindications to endoscopy or anesthesia; 3. Those with coagulation dysfunction; 4. Abdominal pain caused by functional gastrointestinal disease; 5. Join other clinical trials 3 months before the disease; 6. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of catheter-guided mini-forceps biopsy or biliary brush cytology findings;Sensibility;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Technical success rate;Adverse event occurrence rate; | — |
Countries
China
Contacts
Public ContactLi Baiwen
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed