dry eye disease
Conditions
Interventions
experimental group:The trial drug was used twice
Sponsors
Xiamen Eye Center of Xiamen University
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 16 years old, gender unlimited; 2. Patients complain of dry eyes, and EDS (Eye Dryness Score) refers to dry eyes score (VAS evaluation of 0-100 points) >=40 points; 3. Chinese Dry eye Questionnaire >=7 points 4. FBUT=1 point 6. Volunteer to participate in the study and sign a written informed consent
Exclusion criteria
Exclusion criteria: 1. Have an uncontrolled active eye disease that may affect the reliability of observations in this clinical trial, e.g Combined with infectious conjunctival keratitis, uveitis, nasolacrimal duct obstruction, intraocular infection, etc. 2. Fluorescein corneal staining completely fused into patches or the appearance of filamentous keratitis 3. Patients who used topical cyclosporins within 2 weeks 4. Patients with a history of allergies to any component of drugs or tests (e.g., cyclosporine, luciferin, etc.) intended for use in the study 5. Patients with exophthalmos or incomplete eyelid closure 6. Patients with uncontrolled systemic disease or for other reasons deemed unsuitable for admission to the study by the investigator 7. Pregnant women, lactating women, women of childbearing age who do not take effective contraceptive measures, or plan to conceive during the test period, and the pregnancy test results are positive before the test; 8. Patients who were unwilling to stop wearing contact lenses during the study 9. Patients who have participated in or are participating in other clinical trials within 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| EDS at 24 weeks; | — |
Countries
China
Contacts
Public ContactZuguo Liu
Xiamen Eye Center of Xiamen University
Outcome results
None listed