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The prediction of fluid response by changes in hemodynamic dynamic indicators caused by lung recruitment maneuver during one-lung ventilation in pediatric .

The prediction of fluid response by changes in hemodynamic dynamic indicators caused by lung recruitment maneuver during one-lung ventilation in pediatric .

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070690
Enrollment
Unknown
Registered
2023-04-20
Start date
2023-04-20
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

scheduled for elective surgery under general anesthesia

Interventions

Gold Standard:Clinical outcome(Changes in hemodynamic parameters caused by one-lung ventilation, such as changes in indicators, SVV, SV, MAP, PPV, etc.)
Index test:Changes in hemodynamic parameters using lung recruitment maneuver during one-lung ventilation?

Sponsors

Shanghai Children's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 6 Years

Inclusion criteria

Inclusion criteria: (1) Age <= 7 years old. (2) Invasive arterial blood pressure. (3) Use lung protective ventilation. (4) Patients undergoing elective surgery undergoing single lung ventilation. (5) Obtain permission from parents or guardians (sign informed consent form).

Exclusion criteria

Exclusion criteria: (1) Preoperative arrhythmia. (2) Right heart dysfunction. (3) Patients with spontaneous ventilation. (4) Ventricular ejection fraction<30%. (5) Obvious respiratory system diseases. (6) Hemodynamic instability. (7) Parents or legal guardians of the child refuse.

Design outcomes

Primary

MeasureTime frame
stroke volume;heart rate;systolic blood pressure;diastolic blood pressure; mean blood pressure;Sensitivity, SE;Specificity, SP;Positive predicative value, PPV;

Secondary

MeasureTime frame
pulse pressure variation;stroke volume variation;Cardiac index, CI;

Countries

China

Contacts

Public ContactYing Sun

Department of Anesthesiology, Shanghai Children's Medical Center

yingsun821@163.com+86 13621738118

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026