Study on comfort during cesarean section
Conditions
Interventions
ND group: Nalbuphine combined with dexmedetomidine group:Intravenous nalbuphine + dexmedetomidine pump
N group: nabulphine group:Intravenous Nalbuphine + dexmedetomidine pump,
Group D: dexmedetomidine group:Intravenous normal saline + dexmedetomidine pump
Sponsors
Taizhou People's Hospital Affiliated to Nanjing University of Chinese Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: ASA grade I and II; Age: 20 ~ 40 years old; BMI between 19 and 39kg/ m2; The maternal sign the informed consent voluntarily; Preoperative routine examination showed no obvious abnormality. No contraindications to lumbar epidural anesthesia; Operation time 37 weeks.
Exclusion criteria
Exclusion criteria: The blocking level exceeds T4 or is less effective; Sinus bradycardia; Allergies to the drugs used in this study; A history of chronic pain, long-term use of opioid analgesics or NSaids; Intraoperative blood loss greater than 800mL; Suffering from mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of intraoperative nausea and vomiting;Traction response grading;Grading of chills reaction;Intraoperative Ramsay Sedation score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incision pain at rest 24 hours after operation;Tocodynia at rest;Incision pain during exercise;VAS pain scores for tocolytic pain during exercise;Qor40 score on postoperative day;sleep quality;Comfort score;IL-6 and CRP levels;Lactation initiation time;Lactation volume score;Postoperative adverse effects; | — |
Countries
China
Contacts
Public ContactJiangbingxue
Taizhou People's Hospital Affiliated to Nanjing Medical University
Outcome results
None listed