Diabetic Retinopathy
Conditions
Interventions
Treatment group(1.0W/cm2):low-intensity pulse ultrasound treatment (1.0W/cm2)
Treatment group (0.5W/cm2):low-intensity pulse ultrasound treatment (0.5W/cm2)
control:none
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Patients diagnosed as non-proliferative diabetic retinopathy by fundus fluorescein angiography; (2) Patients diagnosed as proliferative diabetic retinopathy by fundus fluorescein angiography have no vitreous hemorrhage, proliferative membranes, or traction retinal detachment; (3) Patients aged 18-70 years old and volunteer to participate. Patient or patient's family agrees and signs an informed consent form; (4) Patients are able to cooperate with various studies in clinical trials.
Exclusion criteria
Exclusion criteria: (1) Patients with proliferative diabetic retinopathy who need vitrectomy according to clinical judgment; (2) Patients who were scheduled to undergo anti-VEGF therapy or retinal laser photocoagulation therapy at the time of enrollment; (3) Patients with diabetic macular edema; (4) Patients with refractive medium opacity; (5) Pre-exsiting ophthalmic diseases: glaucoma, other fundus diseases except diabetes retinopathy; (6) Previous intraocular surgery history; (7) Patients with poor compliance; (8) Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| retinal blood flow density;result of multifocal electroretinogram; | — |
Secondary
| Measure | Time frame |
|---|---|
| best corrected visual acuity;Number of retinal microangiomas;areas of retinal non-perfusion;areas of foveal avascular zone;Choroidal capillary blood flow density; | — |
Countries
China
Contacts
Public ContactLu Xinmin
Shanghai Sixth People's Hospital
Outcome results
None listed