Diagnostic value of non-invasive airway inflammation assessment for early chronic obstructive pulmonary disease (COPD)

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300070659

Enrollment

Unknown

Registered

2023-04-19

Start date

2023-04-20

Completion date

Unknown

Last updated

2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease (COPD)

Interventions

early COPD group:No

stable COPD group:No

Control group:No

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with stable COPD: after inhaling bronchodilators, the pulmonary function conformed to FEV1/FVC = 0.8 after inhaling bronchodilators. 4. Provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. Suffer from diseases that clinicians believe may lead to abnormal lung function, such as lung cancer, bronchiectasis, interstitial lung disease, previous history of chest surgery, etc. 2. Who is participating in other interventional clinical studies. 3. Other serious diseases in the past 3 months were hospitalized within 1 month. 4. Those who are unable to cooperate to complete the examination of lung function, etc. 5. Unable to provide written informed consent.

Design outcomes

Primary

Measure	Time frame
Exhaled nitric oxide (FeNO);Exhaled carbon monoxide (FeCO);Exhaled hydrogen sulfide ;	—

Secondary

Measure	Time frame
Inflammatory indicators;Biochemical parameters;Imaging studies and symptom scoring;	—

Countries

China

Contacts

Public ContactZhihong Shi

The First Affiliated Hospital Xi'an Jiaotong University

docszh@163.com+86 18991232195

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026