Clinical study of low-dose radiation therapy for severe/critical infection of COVID-19

Clinical study of low dose radiation therapy for severe/critical infection of COVID-19

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300070643

Enrollment

Unknown

Registered

2023-04-19

Start date

2023-01-20

Completion date

Unknown

Last updated

2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe pneumonia caused by COVID-19

Interventions

Experimental group:Low-dose radiation therapy (LDRT)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age: =18 years old. 2. Gender is not limited. 3. CT or chest radiograph: Inflammatory exudation in both lungs. 4. Nasal catheter oxygen saturation =93%, oxygenation index less than 200mmHg, nasal high flow or non-invasive/invasive assisted mechanical ventilation. 5. The effect of medical treatment is not good, and lung inflammation is progressing rapidly. 6. The patient's family members signed the informed consent voluntarily.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women. 2. Patients with greater life risk during radiotherapy. 3. Patients whose family members refuse to sign the informed consent form. 4. Other situations that the researcher thinks are not suitable for enrollment.

Design outcomes

Primary

Measure	Time frame
Average length of stay;survival rate;Time of weaning from oxygen inhalation after radiotherapy;	—

Secondary

Measure	Time frame
C-reactive protein (CRP);chest CT or chest radiograph;Coagulation index;Glasgow Coma Scale;Routine blood test;SaO2 or PaO2;	—

Countries

China

Contacts

Public ContactWang Jian

Jiangyin People's Hospital

1627879372@qq.com18921239883

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026