Stroke
Conditions
Interventions
Group 1:General walking training
Group 2:based on lower extremity exoskeleton walking training
Sponsors
Zhejiang Rehabilitation Medical Center
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) meet the diagnostic criteria for ischemic stroke in the China Acute Ischemic Stroke Diagnosis and Treatment Guidelines 2018 and for hemorrhagic stroke in the China Acute Hemorrhagic Stroke Diagnosis and Treatment Guidelines 2019; (2) patient is 20-75 years old, first onset, onset = 1 month; (3) mild paralysis of one limb, modified Ashworth classification of the affected lower limb = II; (4) clear consciousness, no obvious cognitive abnormalities, patient can understand and actively participate in the rehabilitation training; (5) no use of drugs affecting balance or walking, such as sedative-hypnotic drugs or antiepileptic drugs.
Exclusion criteria
Exclusion criteria: (1) combined with severe cardiac, pulmonary, hepatic, renal and other important organ insufficiency; (2) combined with severe complications (such as hypertensive crisis, myocardial infarction, angina pectoris, persistent seizures, deep vein thrombosis of lower extremities, etc.); (3) history of cognitive impairment, or sensory loss, or neurological disorders other than cerebral infarction. Cognitive impairment was defined as a score of <=22 on the Mini- mental state examination (MMSE); (4) patients with visual impairment, unable to see the ground when walking;(5) patients with vestibular organ disease;(6) patients with severe disease, or combined with severe skeletal and muscular diseases, or those who could not cooperate with the completion of training and assessment due to various reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum of brain derived neurotrophic factor ;serum of vessel endotherial growth factor; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-Meyer lower extremity motor function score;Tinetti Balance and Gait Scale;FAC Functional Walking Performance Scale;6-minute walk test;ADL scale; | — |
Countries
China
Contacts
Public ContactJifang Qiu
Zhejiang Rehabilitation Medical Center
Outcome results
None listed