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Exploration of acupuncture combined with application therapy in the treatment of allergic rhinitis based on the inflammatory state of the body and the nasopharynx flora

Exploration of acupuncture combined with application therapy in the treatment of allergic rhinitis based on the inflammatory state of the body and the nasopharynx flora

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070627
Enrollment
Unknown
Registered
2023-04-18
Start date
2023-04-20
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

allergic rhinitis

Interventions

treatment group:Acupuncture combined with acupoint application
control group:sham acupuncture combined with acupoint application

Sponsors

Zhejiang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) There are two or more symptoms, such as sneezing, clear water like mucus, nasal congestion, and nasal itching, and the symptoms persist or accumulate for more than 1 hour every day. It may be accompanied by eye itching, conjunctival congestion and other eye symptoms; (2) Pale and edema of nasal mucosa and watery secretion of nasal cavity are common; (3) Serum specific IgE was positive; (4) Age: 18-65 years old, regardless of gender and nationality; (5) No clinical trial has been accepted within 3 months, and no antihistamines or nasal steroids have been taken within 1 month; (6) Those who are willing to accept this treatment and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Only one of the symptoms, such as sneezing, clear water like mucus, nasal congestion and itching, lasts or accumulates for less than 1h every day; (2) The symptoms of pale and edema of nasal mucosa are not obvious; (3) Diagnosed as atrophic rhinitis, hypertrophic rhinitis, vasomotor rhinitis, acute and chronic sinusitis, nasal polyps, severe deviation of nasal septum, eosinophilia and non-allergic rhinitis; (4) Have asthma, urticaria and other allergic diseases. People with stuffy nose, runny nose and sneeze due to cold; (5) Those who use antibiotics and antiallergic drugs, those who are complicated with infection and easy to bleed, and those who have serious diseases such as cardio-cerebrovascular, liver, kidney and hematopoietic system; (6) Pregnant or lactating women, psychotic patients, malignant tumor patients; (7) Poor compliance, or other conditions unsuitable for acupuncture and application. The necessary number of participants will be registered at baseline.

Design outcomes

Primary

MeasureTime frame
score of rhinitis symptoms (RS);serum eotaxin, galactin-10 and nasal lavage eotaxin;Nosopharynx flora;

Secondary

MeasureTime frame
total nasal symptoms score (TNSS);Rhinoconjunctivitis Quality of Life Questionnaire score (RQLQ score);

Countries

China

Contacts

Public ContactYufang Lin

Zhejiang Hospital

314450783@qq.com+86 17816855809

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026