cardiogenic shock
Conditions
Interventions
Haemodynamic monitoring group:1. Head high, foot low position 15 degrees for 1 minute (baseline 1), recording baseline haemodynamic parameters
2. Trendelenburg position: for 3 minutes, recording haemodynamic parameters
3. Return to initial position (baseline 2) and record haemodynamic parameters
4. Perform volume loading test (NS 500ml infusion for 30 minutes) and record haemodynamic parameters.
Sponsors
Zhongshan Hospita, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Receiving VA-ECMO support 2. ECMO flow rate: 2-3L/min 3. Receiving invasive mechanical ventilation 4. Require fluid therapy which was decided by ICU physician to (hypotension, hypoperfusion or attempt to reduce vasoactive drugs)
Exclusion criteria
Exclusion criteria: 1. Age less than 18 years 2. Pregnant or planning to become pregnant, and breastfeeding women 3. Pulseless (pulse pressure difference less than 15 mmHg) 4. moderate to severe aortic valve insufficiency 5. Contraindications to Trendelenburg (abdominal hypertension, gastric retention, etc.) 6. Active haemorrhage 7. Cardiac arrhythmia 8. Unstable ECMO flow 9. Poor ultrasound translucency 10. Participant in other clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perfusion Index;cardiac output; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;central venous pressure;Blood gas analysis; | — |
Countries
China
Contacts
Public ContactGuowei Tu
Zhongshan Hospital, Fudan University
Outcome results
None listed