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Clinical study of ultrasound measurement of lumbar dural length to predict ropivacaine ED50 for epidural labor analgesia

Predicting the ED50 of ropivacaine for epidural analgesia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070614
Enrollment
Unknown
Registered
2023-04-18
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epidural labor analgesia

Interventions

Intervention group:Ropivacaine dose

Sponsors

Nanjing Maternity and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Pregnant women aged 18–45 years old who are suitable for natural childbirth; 2. Having good coordination degree; 3. ASA classification: I-II; 4. Single fetus full-term pregnancy.

Exclusion criteria

Exclusion criteria: 1. Exclusions before inclusion: (1) There are contraindications related to epidural anesthesia; (2) Combined cardiovascular and cerebrovascular diseases, respiratory disease, and hepatorenal system disease; (3) Previous history of intraspinal anesthesia. 2. Exclusions after inclusion: (1) Failure of epidural puncture; (2) those at risk for spinal anesthesia; (3) The planes of bilateral sensory blocks are not uniform; (4) Researchers who switched to cesarean section and did not complete it.

Design outcomes

Primary

MeasureTime frame
VAS score;Lumbar dural length;

Secondary

MeasureTime frame
Spine length;Height;Body weight;Episodes of adverse events such as apnea, hypoxemia, bradycardia, hypotension and nausea and vomiting;

Countries

China

Contacts

Public ContactShanwu Feng

Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital

shanwufeng666@163.com+86 13921426351

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026