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Effect and mechanism of low-frequency rTMS on motor function recovery after stroke through interhemispheric inhibition

Effect and mechanism of low-frequency rTMS on motor function recovery after stroke through interhemispheric inhibition

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070578
Enrollment
Unknown
Registered
2023-04-17
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular disease

Interventions

Group of rTMS:repetitive transcranial magnetic stimulation
Group of sham:sham stimulation

Sponsors

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1: confirmed clinical stroke diagnosis, which was based on the Fourth National Conference on Cerebrovascular Diseases 2: the first ischemic or hemorrhagic stroke confirmed by CT or MRI scans 3: Unilateral onset, course of disease 2 weeks to 1 year 4: Brunnstrom of hemiplegic upper limb and hand staging from 4 to 5 5: Mini Mental State Examination (MMSE) > 20/30 6: informed consent to the study and signed the consent of rTMS.

Exclusion criteria

Exclusion criteria: 1: With progressive stroke, malignant progressive hypertension and so on 2: The function of heart, lung, liver, kidney and other important organs is reduced or failed 3: Aphasia, hemianopsia, hemianopsia, or affective disorders, which affected participants' ability to follow study procedures 4: Known risk factors for TMS, such as pacemakers, intracranial metal implants, epilepsy, and skull defects.

Design outcomes

Primary

MeasureTime frame
Fugl—Meyer Assessment;Grip strength;

Secondary

MeasureTime frame
Interhemispheric Inhibition;Hemispheric asymmetry index;Laterality Index;Action Research Arm Test;Modified Barthel Index;

Countries

China

Contacts

Public ContactQing Xie

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

ruijin_xq@163.com+86 18845145202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026