Frailty
Conditions
Interventions
Experimental group:muscle-building and anti-frailty exercise
Control group:health education
Sponsors
The Second Medical Center, Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
70 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 70 years old; 2. Diagnosed as asthenic or pre-asthenic; 3. Volunteer to participate in the trial and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe cognitive impairment; 2. Severe loss of vision and hearing, unable to communicate normally; 3. Those who have suffered from major diseases or have not recovered from major surgery within the past six months; 4. Acute stage of various diseases or stage of severe functional failure, such as acute infection, gastrointestinal bleeding, heart failure, respiratory failure, renal failure, etc.; 5. People with diabetes (fasting blood sugar level > 125 mg/dl), high blood pressure, and heart disease that have not been effectively controlled; 6. Patients whose functional tests are affected by pain in limb joints, bones, muscles, etc.; 7. Patients with internal metal implants such as cardiac pacemakers and artificial joints.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Short Physical Performance Battery (SPPB);Fried scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| body composition;Activities of daily living (ADL);Mini-Mental State Examination (MMSE);The Geriatric Depression Scale (GDS-15);Interleukin-6;Tumor necrosis factor-alpha;Chemokine -9;cystatin C;Vitamin D;Insulin growth factor 1; | — |
Countries
China
Contacts
Public ContactPeng Nan
The Second Medical Center, Chinese PLA General Hospital, Beijing, China
Outcome results
None listed