disturbance of consciousness
Conditions
Interventions
control group:Routine rehabilitation
ta VNS group:Vagus nerve stimulation
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: ? Age > 18 years old, duration > 28 days; ? According to the CRS-R scale, it was diagnosed as VS or MCS in pDOC; ? No history of epilepsy or other neuropsychiatric diseases; (4) No implant medical equipment such as skull repair materials, shunt devices, aneurysm clips, deep electrodes, etc.; (5) Stable intracranial condition, no obvious cerebral edema, no severe cerebral atrophy; The patient's family members get the right to know, and voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: ? A history of tumor; ? History of severe arrhythmia or pacemaker implantation; (3) previous history of vagus nerve function injury; (4) Patients with severe intracranial infection; (5) Other situations unsuitable for ta VNS intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glasgow coma scale, GCS; | — |
Secondary
| Measure | Time frame |
|---|---|
| coma recovery scalerevised;P300 test;f NIRS detection; | — |
Countries
China
Contacts
Public ContactLiu Yong
Zhejiang Provincial People's Hospital
Outcome results
None listed