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An Early Warning System Strategy for Pulse Perfusion Index Combined With Interleukin-6 to Assess Local Anesthetic Dose and Adverse Effects in Labor Epidural Anesthesia

An Early Warning System Strategy for Pulse Perfusion Index Combined With Interleukin-6 to Assess Local Anesthetic Dose and Adverse Effects in Labor Epidural Anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070517
Enrollment
Unknown
Registered
2023-04-14
Start date
2023-04-20
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epidural related maternal fever

Interventions

Treatment group :Reduce the concentration of local anesthetic so that PI value < warning value The women whose PI value exceeded the warning value 30 minutes after analgesia were randomly divided into
Non-treatment group :Women with PI values above the alert value after 30 minutes of analgesia were randomly divided into treatment and non-treatment groups, with no reduction in maternal local anesthe

Sponsors

Affiliated People's Hospital of Jiangsu University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Primigravida intended for vaginal delivery, receiving epidural labor analgesia, full-term singleton

Exclusion criteria

Exclusion criteria: Cardiopulmonary disease (including hypertension), history of endocrine disease (including diabetes), maternal temperature = 37.5 °C before analgesia, BMI = 30, clearly diagnosed chorioamnionitis, first stage of labor = 10 h, repeated cervical examinations

Design outcomes

Primary

MeasureTime frame
Pleth perfusion index;Interleukin 6;Ear temperature;

Secondary

MeasureTime frame
Anesthesia level determination;visual analogue scale ;Neonatal Apgar score;Contraction monitoring;Childbirth endings;

Countries

China

Contacts

Public ContactSun Caixia

Affiliated People's Hospital of Jiangsu University

suncaixia_zj@126.com+86 13952854371

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026