H-type hypertension
Conditions
Interventions
treatment group:Jiangyitongmai formula
Control group:Placebo
Sponsors
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) It meets the diagnostic criteria for H-type hypertension, and the blood pressure level is grade-1 and grade-2; (2) It meets the diagnostic criteria for Tanyuhujie sysdrome; (3) It meets the diagnostic criteria for carotid atherosclerosis, carotid artery ultrasound indicated that the thickness of carotid intima-media was =1.0mm; (4) Aged 30-75 years old; ? Volunteer to participate in the experiment and sign the informed consent.
Exclusion criteria
Exclusion criteria: ? Can not cooperate; ? Secondary hypertension; (3) Patients who ccombined with severe cardiovascular and cerebrovascular diseases, such as acute myocardial infarction, acute heart failure, stroke, unstable angina, active myocarditis or pericarditis; Patients who had received PCI or CABG within 90 days prior to inclusion or expected to receive PCI or CABG within 90 days. (4) Patients who received infectious diseases; ? Patients who had severe impairment of liver and kidney function (serum ALT 3 times higher than the normal value; Cr > 1.5 times the upper limit of normal reference value). ? Patients who had serious hematologic disease, serious mental illness, connective tissue disease or malignant tumor; ? Possible or confirmed allergy to the test ingredient; ? if the duration of taking statin is less than 6 months before joining the group; (9) Women during the period of pregnancy, planned pregnancy, or lactation; (10) Patients who is currently participating in other studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endothelium function and inflammatory factor; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure variability;Serum homocysteine;Serum lipid;Carotid artery ultrasound;TCM syndrome score; | — |
Countries
China
Contacts
Public ContactDuan Wenhui
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed