Skip to content

The mechanism study of exosomal circWSB1 promotes TKI resistance in renal cell carcinoma by regulating glycolysis

The mechanism study of exosomal circWSB1 promotes TKI resistance in renal cell carcinoma by regulating glycolysis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070501
Enrollment
Unknown
Registered
2023-04-13
Start date
2023-04-14
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Carcinoma

Interventions

Experimental Group:none

Sponsors

Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. When signing the informed consent form, the age is equal to or greater than 18 years old and less than 90 years old. 2. Patients diagnosed with renal cell carcinoma through puncture/surgical pathology. 3. The expected survival period is>12 months. 4. The ECOG score is 0-2 points. 5. The patient agrees and has the ability to follow the planned research visit, provide surgical samples, and cooperate with other research steps. 6. The patient has normal organ function, with WBC = 3000/mm3 or absolute neutrophil count = 1500/mm3, and AST and ALT below 1.5 ULN.

Exclusion criteria

Exclusion criteria: 1. Researchers have determined that patients may have other serious diseases that may affect follow-up and short-term survival, and any medical reasons that indicate a significant risk of death during the one-year study period. 2. Those who have had any other malignant tumors within the past 3 years prior to enrollment. 3. Unable to obtain clinical information required for the study. 4. Other researchers believe that it is not suitable for enrollment.

Design outcomes

Primary

MeasureTime frame
Transcriptome sequencing;

Secondary

MeasureTime frame
clinical stage;pathological stage;

Countries

China

Contacts

Public ContactLin Qi

Xiangya Hospital of Central South University

linqi1212@126.com+86 13975196398

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026