Post-stroke hemiplegia
Conditions
Interventions
Healthy group:navigated-rTMS and non-navigated-rTMS
Poststroke hemiplegia group:non-navigated-rTMS
Sponsors
Chengdu Sport University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Healthy adult subjects were recruited from Qingshuihe Campus of UESTC. The inclusion criteria are: (1) Aged 18-30 years, half male and half female, right-handed; (2) No history of substance abuse, consent to rTMS intervention, and pass TMS safety screening; (3) No epilepsy or other neuropsychiatric diseases in the past; (4) No motor system disease; (5) No MRI scan contraindications, no history of head trauma or heart disease; (6) The head motion amplitude of all fMRI images was translational < 1mm and rotational < 1 degree. 2. Stroke patients are to be recruited from the Sports Hospital affiliated to Chengdu Physical Education University. The inclusion criteria were 30 to 70 years old, and included criteria included: (1) Primary onset, non-lateral motor area stroke lesion, course of disease 2 weeks to 3 months; (2) Hemiplegia with unilateral hemispheric injury; (3) Brunnstrom classification (Brunnstrom, 1966)<= stage IV; (4) Agree to receive rTMS treatment on the basis of conventional treatment, pass TMS safety screening, and have no previous epilepsy and other neuropsychiatric diseases, no other motor system diseases; (5) No MRI scan contraindications, no history of head trauma or serious heart disease; (6) Unconscious disorder; (7) Can cooperate with the subject to complete scale evaluation, MRI scanning and TMS treatment; (8) The head motion amplitude of all fMRI images was translational < 2mm and rotational < 2 degrees; (9) No muscle relaxation drugs have been taken recently.
Exclusion criteria
Exclusion criteria: 1. Severe complications (including renal and liver insufficiency, myocardial infarction, heart failure, gastrointestinal bleeding, severe infection, mental disorders and dementia, epilepsy, osteoarthropathy, etc.); 2. Have obvious consciousness or mental abnormality; 3. Claustrophobic; 4. Patients with cardiac pacemakers installed in their bodies; 5. Can't cooperate; 6. Pregnant patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| brain imaging;clinical assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| brain functions imaging; | — |
Countries
China
Contacts
Public ContactWang Jue
Chengdu Sport University
Outcome results
None listed