mild to moderate ulcerative colitis
Conditions
Interventions
Experimental group:Mesalazine combined with percutaneous auricular vagus nerve stimulation
Control group:Mesalazine combined with sham transcutaneous ear vagus nerve stimulation
Sponsors
Anhui Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients meeting UC (mild to moderate) diagnostic criteria; 2. Aged range from 18 to 65 years, gender is not limited; 3. Voluntarily accept the drug treatment, and sign the informed consent, and the informed consent process complies with relevant provisions of GCP.
Exclusion criteria
Exclusion criteria: 1. Patients with cardiovascular, cerebrovascular, liver, kidney, hematopoietic system diseases, hyperthyroidism, diabetes and other serious primary diseases, or serious diseases affecting their survival (such as tumors) and psychiatric patients; 2. Patients who are pregnant or planning to be pregnant or lactating; 3. Suspected or confirmed history of alcohol and drug abuse; 4. Those with cognitive dysfunction who cannot give adequate informed consent; 5. Patients who have participated in other clinical trials within the last 1 month; 6. Patients who have had abdominal surgery within 6 months; 7. Patients with general or specific contraindications to the physical therapy provided; 8. Patients with factors deemed unsuitable for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale/Score;Bristol Stool Characterization Scale;Serum neurotransmitter levels;Inflammatory indicators;Intestinal flora; | — |
Secondary
| Measure | Time frame |
|---|---|
| Autonomic function;Vital signs;Adverse effects; | — |
Countries
China
Contacts
Public ContactYu Yue
Anhui Provincial Hospital
Outcome results
None listed