HBV-related hepatocellular carcinoma
Conditions
Interventions
TDF Group:None
Sponsors
The Third Affiliated Hospital of Naval Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Histopathologically confirmed hepatitis B associated hepatocellular carcinoma in patients aged 18-80 years with hepatitis B associated hepatocellular carcinoma; 2. Radical surgical resection was performed (no tumor residue was found in the remaining liver and other parts, and no tumor cells were found in the pathological margin); 3. Start receiving ETV or TDF as antiviral therapy before surgery or within 1 month after surgery; 4. Continuous antiviral therapy after surgery.
Exclusion criteria
Exclusion criteria: 1. There are other histopathological tumors other than hepatocellular carcinoma; 2. History of antiviral therapy other than TDF and ETV; 3. Other types of hepatitis B virus infection; 4. Patients with portal vein cancer thrombus or hepatic vein cancer thrombus or extrahepatic metastasis; 5. Follow-up time was less than 3 months; 6. Patients who have received antiviral therapy for more than 3 months before the diagnosis of HBV-associated HCC or started antiviral therapy for more than 1 month after surgery; 7. Patients with hepatectomy and tumor ablation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| date of recurrence;date of death;anti-viral drugs for HBV; | — |
Secondary
| Measure | Time frame |
|---|---|
| age;sex;HbsAg;HbsAb;HbeAg;HbeAb;HbcAb;HBV-DNA;alpha-fetoprotein;platelets;total bilirubin;alanine aminotransferase;albumin;prothrombin time;tumor diameter;multiple tumors;tumor capsule;cirrhosis degrees;resection margin;microvascular invasion;date of operation;intraoperative blood loss volume;intraoperative blood transfusion volume; | — |
Countries
China
Contacts
Public ContactHuang Gang
The Third Affiliated Hospital of Naval Medical University
Outcome results
None listed