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Detection of plasma non-coding RNA in patients with premature coronary heart disease

Detection of plasma non-coding RNA in patients with premature coronary heart disease

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070484
Enrollment
Unknown
Registered
2023-04-13
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

premature coronary artery disease

Interventions

Early onset coronary heart disease group:none
Late onset coronary heart disease group:none
Healthy group:none

Sponsors

University of South China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with coronary heart disease were diagnosed according to the Diagnostic Criteria for Coronary atherosclerotic Heart Disease, and coronary angiography results showed that at least one vessel had stenosis >=50%. 2. Age of male patients <=55 years old and female patients <=65 years old. 3. Follow doctor's orders and managers. 4. Informed consent, sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who received coronary vascular reconstruction within 6 months. 2. Patients not diagnosed with coronary heart disease for the first time and taking drugs for a long time. 3. Patients with other heart diseases, such as arrhythmia, atrial fibrillation, valvular heart disease, and heart failure. 4. Patients with hematologic diseases, malignant tumors, rheumatic immune system diseases, kidney diseases, liver diseases. 5. Patients with serious systemic diseases, such as severe infection and severe burn, who have undergone surgery within one month. 6. Hemolysis caused by improper preservation of blood samples.

Design outcomes

Primary

MeasureTime frame
No-coding RNA biomarker;

Secondary

MeasureTime frame
Cardiac ultrasound;

Countries

China

Contacts

Public ContactJiang Zhisheng

University of South China

zsjiang2005@163.com+86 13707349803

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026