Chronic kidney disease
Conditions
Interventions
Erythropoietin group:NA
Sponsors
Deyang People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years, dialysis 3 times a week, 3-4 hours each time, dialysis time >=3 months (Kt/V > 1.2, URR > 65%); 2. In patients diagnosed with renal anemia who were treated with rosalrestat or erythropoietin, Hb was controlled at 100-130g/L after treatment; 3. Clear consciousness, no mental dysfunction, can accurately express their own will; 4. All patients signed informed consent with complete clinical data.
Exclusion criteria
Exclusion criteria: 1. Anemia caused by diseases other than CKD, such as pure red cell aplastic anemia and myelodysplastic syndrome; 2. Patients with malignant tumors that affect their survival; 3. Poor compliance; 4. Any other circumstances in which the investigator considers the subject unable to participate in the study; 5. Patients with previous cerebrovascular disease or myocardial infarction; 6. Dementia patients; 7. Use of benzodiazepines; 8. A history of mental illness, such as depression or schizophrenia; 9. Patients have sensory (visual and auditory) or motor impairments that prevent them from completing tests that require these senses; 10. The patient has a life expectancy of less than 6 months, is scheduled for a kidney transplant within the baseline 6 months, or is expected to have a recovery of kidney function; 11. Severely impaired liver function; 12. Patients during lactation and pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ß amyloid;Phosphorylated TaU-181 protein;Hypoxic inducible factor-1 a;Disintegrin-like metalloproteinase 10;Montreal Cognitive Assessment Scale; | — |
Countries
China
Contacts
Public ContactLiu Minglin
Deyang People's Hospital
Outcome results
None listed