Circadian rhythm disturbance
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years; 2. American Society of Anesthesiologists (ASA) Levels I to III; 3. Return to the general ward after surgery.
Exclusion criteria
Exclusion criteria: 1. Patients with Parkinson's disease, dementia (including dementia caused by Parkinson's disease, Alzheimer's disease and dementia with Lewy bodies) or mental illness; 2. Patients who are unable to communicate due to severe audio-visual impairments, language barriers and/or communication difficulties; 3. Alcohol dependence and drug addiction; 4. Oral diseases; 5. Shift workers; 6. Unexpected discharge or refusal to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plasma melatonin level;saliva melatonin level; | — |
Secondary
| Measure | Time frame |
|---|---|
| sleep quality;the intensity of pain at rest and with movement;body temperature;blood pressure;anxiety; depression;plasma cortisol level;saliva cortisol level; | — |
Countries
China
Contacts
Peking University Third Hospital